Metware Biotechnology Co., Ltd.
T500

T500

t500 targeted metabolomics service

T500 is a targeted-metabolomics method that are both extensive and accurate in identification and quantification of 540 disease-related metabolites. Each metabolite is matched and quantified to chemical standards to obtain absolute quantification.

Technology Introduction

T500 is our most comprehensive targeted-metabolomics service that is both extensive and accurate in the identification and quantification of 540 well-known metabolites. These metabolites were chosen for their close association with various neurological diseases, metabolic diseases, gastrointestinal diseases, lung diseases, reproductive diseases, liver diseases, and cancer.

Metabolic Disease Metabolites

Technical Features of T500 Targeted Metabolomics Service

Only Need One

Only one sample needed, saves time and avoids collecting large number of replicates.

Wide Coverage

540 metabolites in 9 metabolic pathways. 

Absolute Quantification

using 540 standard curves with r > 0.99.

Project Workflow of T500 Targeted Metabolomics Service

Project Workflow of T500 Targeted Metabolomics Service

List of Metabolites

Metabolite speciesNORepresentative metabolites
Amino acids and their derivatives71L-Leucine,Phenylalanine,Tyrosine,Histidine,Xanthurenic Acid
Nucleotide and  Its metabolomics92Inosine,dTMP,dUMP,Guanine,Adenosine
Organic acid And Its derivatives66Citric acid,Salicylic acid,Hippuric acid,Fumaric acid,Sebacic acid
Hormones and hormone related compunds50Pregnenolone,Testosterone,Cortisone,Melatonin,Hydroxyecdysone
Benzene ring compounds45Phenylethylamine,Phthalic acid,Tyramine,Diphenylamine,1H-pyrrole
Bile acids39Lithocholic acid,Hyodeoxycholic acid,Glycocholic acid,omega-muricholic acid,Taurocholic acid
Amines32Tryptamine,Spermidine,Hexylamine,Butylamine,Aniline
CoEnzyme and vitamins20Vitamin B9,Pyridoxal hydrochloride,Pyridoxamine dichlorohydrate,vitamin B1,Retinoic acid
Carbohydrates and Its metabolites153-Phosphoglyceric acid,Mannose,2-Amino-2-deoxymannose,Xylonate,D-Glucose 6-phosphate
Indole and Its derivatives14Methyl indole-3-acetate,Indole-3-acetamide,2-indolecarboxylic acid,5-Hydroxyindoleacetic Acid,3-Methyloxindole
CAR142-Methylbutyroylcarnitine,L-palmitoylcarnitine,Isovaleryl-carnitine,Isobutyryl-L-carnitine,Dodecanoylcarnitine
FFA122-Hydroxyhexadecanoic acid,Octadecanedioate (C18),Hexadecanedioic acid,12-Hydroxyoleic acid,Transvaccenic Acid (C18:1T)
Oxidized lipids112,13-DiHOME
Other69Myo-Inositol,Betaine,ADP,2-Picolinic Acid


T500 metabolite-related diseases (partial)

metabolitesCritical illnesses
InosineCanavan disease; Kidney disease; Purine nucleoside phosphorylase deficiency; Thymidine treatment; Septic shock; Xanthinuria type 1; Degenerative disc disease; Irritable bowel syndrome; Colorectal cancer; Crohn's disease; Ulcerative colitis; Gout; Coronary artery disease; Attachment loss; Periodontal Probing Depth; Tooth Decay; Eosinophilic esophagitis
3-phenyllactic acidColorectal cancer; Attachment loss; Periodontal Probing Depth; Supragingival Plaque; Phenylketonuria
Xanthurenic AcidHemodialysis; Colorectal cancer; Kynureninase deficiency; Eosinophilic esophagitis
Quinolinic AcidNicotinamide Adenine Dinucleotide Deficiency; Uremia; Hepatic coma;T raumatic brain injury; Hydrocephalus; Intraventricular hemorrhage; CNS tumors; CNS infections; AIDS;Malaria; Tuberculous meningitis; Anemia; Convulsion; Amyotrophic lateral sclerosis; Sporadic amyotrophic lateral sclerosis; Familial amyotrophic lateral sclerosis; Eosinophilic esophagitis
4-hydroxybenzoic acidSupradiaphragmatic malignancy; Colorectal cancer; Eosinophilic esophagitis
Hippuric acidUremia; Crohn's disease; Ulcerative colitis; Paraquat poisoning; Lung Cancer; Diabetes mellitus type 1; Argininosuccinic aciduria; Propionic acidemia; TyrosinemiaI; Phenylketonuria; Maple syrup urine disease; Eosinophilic esophagitis; Colorectal cancer; Schizophrenia;Obesity
L-Leucic acidColorectal cancer; Supragingival Plaque; Tooth Decay; Maple syrup urine disease; Eosinophilic esophagitis
alpha-Linolenic acidHypertension; Essential hypertension; Major depressive disorder; Isovaleric acidemia; Colorectal cancer;Thyroid cancer
Fumaric acidColorectal cancer; Alzheimer's disease; Irritable bowel syndrome; Diverticular disease; Rheumatoid arthritis; Lung Cancer; Eosinophilic esophagitis; Fumarase deficiency; 2-Ketoglutarate dehydrogenase complex deficiency; Amish lethal microcephaly; Lipoyltransferase 1 Deficiency


Applications of T500 Targeted Metabolomics Service

Applications of T500 Targeted Metabolomics Service
WHAT'S NEXT IN OMICS: THE METABOLOME
WHAT'S NEXT IN OMICS: THE METABOLOME

Please submit a detailed description of your project. We will provide you with a customized project plan metabolomics services to meet your research requests. You can also send emails directly to support-global@metwarebio.com for inquiries.