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support-global@metwarebio.com
Providing energy
provide energy for intestinal mucosal epithelial cells, muscles, kidneys, heart, and brain.
Short-chain fatty acids (SCFAs), also referred to as volatile fatty acids, are organic fatty acids characterized by carbon chains that vary in length from 1 to 6 carbon atoms. They primarily encompass acetic acid, propionic acid, isobutyric acid, butyric acid, isovaleric acid, valeric acid, and hexanoic acid, among others.
Approximately 90% of SCFAs originate in the colon through the fermentation of indigestible carbohydrates by bacteria, while the remainder is produced through dietary intake and protein metabolism. In a healthy human gut, SCFAs are generated at a daily rate of around 50-100 mmol. With our own short chain fatty acid database, MetwareBio offers absolute quantification of 11 molecules in a single run.
provide energy for intestinal mucosal epithelial cells, muscles, kidneys, heart, and brain.
SCFAs can strengthen the intestinal mechanical barrier by increasing mucus secretion, nourishing intestinal epithelial cells, and enhancing tight junction proteins.
They participate in immune regulation within the gut by affecting the release of inflammatory factors, immune chemotaxis responses, and the inhibition of immune effector cell proliferation.
They inhibit the growth and proliferation of colorectal tumor cells, induce tumor cell differentiation, and promote apoptosis.
Inflammatory diseases of the gastrointestinal tract, colon cancer, cardiovascular diseases, brain disorders, kidney diseases, and other related illnesses.
Mechanisms of SCFAs in metabolic regulation and the brain-gut axis.
Research on poultry feed breeding and the development of nutritional products.
Targeting drugs related to gastrointestinal inflammation and the development of dietary supplements.
NO | compounds | NO | compounds |
1 | 2-methylbutyrate | 7 | Isohexanoate |
2 | Acetate | 8 | Isovalerate |
3 | Butyrate | 9 | Octanoate |
4 | Crotonate | 10 | Propionate |
5 | Hexanoate | 11 | Valerate |
6 | Isobutyrate |
Please submit a detailed description of your project. We will provide you with a customized project plan metabolomics services to meet your research requests. You can also send emails directly to support-global@metwarebio.com for inquiries.
