Blog

Isoprenoids Explained: Mevalonate (MVA) vs MEP Pathways, CoQ10 and Dolichol in Health and Disease

Nov 17, 2025

Learn how isoprenoids are built, how MVA vs MEP pathways feed CoQ10, dolichol and protein prenylation, and how to quantify them with targeted metabolomics.

Comprehensive Guide to the Top Clustering Methods for Omics Data Analysis

Nov 11, 2025

Choose the right clustering for omics data—hierarchical, k-means, DBSCAN—plus distance metrics and validation (silhouette, ARI) with practical examples.

Biological Waxes: Composition, Plant Cuticular Waxes, and GC-MS Profiling

Nov 10, 2025

Learn what biological and plant cuticular waxes are, their functions and composition, and how to profile them using GC-MS and GC×GC-MS—from sampling to data interpretation.

How Genomics and Proteomics Work Together in Modern Biology

Nov 07, 2025

Explore how Genomics and Proteomics complement each other in modern biology. Learn how Multi-Omics technologies and professional Proteomics Services transform genomic data into real biological insights for medicine, agriculture, and beyond.

Isobutyric Acid (Isobutyrate): An Overlooked Branched SCFA in Gut Health & Disease

Nov 06, 2025

Learn how isobutyric acid (isobutyrate) signals protein fermentation, how it differs from butyrate, its links to IBD/NAFLD/CRC, and how to measure it (GC–MS vs LC–MS/MS).

Advancing Clinical Research Through Modern Protein Quantification Methods

Nov 05, 2025

Discover how advanced protein quantification methods are revolutionizing clinical research. Learn key technologies, quality control practices, and how expert Proteomics Services can enhance biomarker discovery and therapeutic studies.

ATP vs ADP: Structure, Energy, and What the Ratio Really Tells You

Nov 04, 2025

Differences between ATP and ADP, why ATP/ADP ratio and adenylate energy charge (AEC) matter, and practical measurement methods (luciferase, LC–MS/MS).

t-SNE vs UMAP: A Comprehensive Guide for Visualizing High-Dimensional Omics Data

Nov 03, 2025

Compare t-SNE vs UMAP for high-dimensional omics—when to use each, key parameters, pros/cons, and tips for scRNA-seq, bulk, and spatial data.

Indole: The Microbial Metabolite Connecting Gut Health, Brain, and Immunity

Oct 31, 2025

Understand indole's microbial origin, host metabolism, roles in IBD, brain inflammation & cancer—and how to measure key indole metabolites.

DIP-MS: Ultra-Deep Proteomics Unravels Protein Complexes

Oct 29, 2025

Learn how DIP-MS integrates BN-PAGE, DIA-MS, and deep learning to resolve protein complexes in one shot—benchmark data, case study, and workflow.

Volcano Plots in Metabolomics & Proteomics: Interpretation, Cutoffs, and Best Practices

Oct 28, 2025

Discover how to read volcano plots, set fold-change/q-value cutoffs, avoid pitfalls, and turn results into pathway insights for omics studies.

Trimethylamine N-oxide (TMAO): From Gut Microbiome Pathway to Cardiometabolic Risk

Oct 27, 2025

What is TMAO? Learn how diet, gut microbes and FMO3 shape TMAO levels; evidence for CVD/CKD/diabetes risk; how to lower TMAO; and how targeted LC–MS/MS panels quantify TMAO for research.

LC-MS Made Practical: Principles, Platforms, and a Reproducible Workflow

Oct 24, 2025

Learn how LC-MS really works, when to choose triple quadrupole vs Q-TOF/Orbitrap, and a step-by-step workflow to minimize matrix effects and achieve reliable quantitation—plus real-world omics playbooks.

Methylmalonic Acid: From B12 Deficiency Indicator to Age-Linked Cancer Biomarker

Oct 23, 2025

Learn how methylmalonic acid (MMA) moves from B12 deficiency marker to age-linked oncometabolite, with testing, ranges, renal caveats, and LC–MS/MS tips.

Bile Acids and Human Disease: Metabolism, FXR/TGR5 Signaling, and Clinical Applications

Oct 21, 2025

Mechanisms, pathways, and clinical roles of bile acids—FXR/TGR5 signaling, cholestasis, NAFLD/NASH—and how LC–MS profiling advances research.

Proteomics and Metabolomics in Plant Science: Multi-Omics Innovations in Agriculture

Oct 17, 2025

Learn how proteomics + metabolomics decode plant stress, flavor, and yield—with actionable multi-omics case studies and service workflows.

Proteoforms in Proteomics: Definition, Biological Importance, and Detection Technologies

Oct 16, 2025

Learn what proteoforms are, why they matter, and how DDA, DIA, MRM/PRM, Olink and Simoa detect them for discovery and clinical proteomics.

Sphingosine: What It Is, Biosynthesis, and Roles in Health & Disease

Oct 13, 2025

Learn what sphingosine is, how it’s made and metabolized, how it differs from ceramide/S1P, and why it matters in skin defense, cancer, and neuroinflammation.

Metaproteomics Guide: Turning Microbiome Proteins into Functional Insights

Oct 09, 2025

Metaproteomics explained: workflow, LC-MS/MS, database search, and real-world applications that link microbiome genes to protein function in health, disease, and ecology.

Normality Tests in Statistics: Top Methods and Tools for Reliable Data Analysis

Sep 29, 2025

Learn how to check normality fast: Q–Q/P–P plots, Shapiro–Wilk, K–S, Anderson–Darling. Choose by sample size and run in Python, R, or SPSS.