Spatial Metabolomics

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Spatial Metabolomics in Cancer Research: Unlocking the Metabolic Code for Precision Oncology

Mar 24, 2025

Unlock how spatial metabolomics transforms cancer research by revealing tumor heterogeneity, metabolic vulnerabilities, and novel diagnostic and therapeutic strategies in precision oncology.

How to Choose the Right Spatial Resolution in MSI for Spatial Metabolomics

Apr 08, 2026

Learn how to choose the right spatial resolution in MSI for spatial metabolomics using practical rules, sample-based guidance, and common application examples.

Matrix Spraying for MALDI-MSI Spatial Metabolomics: Challenges, Advances, and Future Trends

Apr 07, 2026

Learn how matrix spraying affects MALDI-MSI spatial metabolomics, and discover new methods that improve sensitivity, reproducibility, and spatial resolution.

How to Choose the Best Matrix for MALDI Spatial Metabolomics

Apr 02, 2026

Learn how to choose the right MALDI matrix for spatial metabolomics based on analytes, ion mode, spatial resolution, and sample availability.

OCT, CMC, FSC22 & Gelatin: Embedding Media for Spatial Metabolomics

Apr 01, 2026

Compare OCT, CMC, FSC22, and gelatin embedding media for spatial metabolomics and MSI. Learn their advantages, limitations, and practical selection guidelines for cryosectioning.

Spatial Metabolomics in Liver Disease Research

Mar 23, 2026

Explore how spatial metabolomics reveals liver zonation, injury patterns, MASH progression, HCC metabolism, and clinical applications in liver disease research.

Spatial Metabolomics (MSI) Metabolite Identification: From Accurate Mass to Evidence-Integrated Annotation

Mar 20, 2026

Learn how metabolite identification works in spatial metabolomics MSI, from accurate mass screening to evidence-integrated annotation using MS/MS, spatial context, and biological validation.

Spatial Metabolomics for Biomarker Discovery in Precision Medicine

Mar 11, 2026

Learn how spatial metabolomics reveals tissue-specific metabolic biomarkers, supports disease stratification, and advances precision medicine.

Tissue Cryosectioning Guide for Spatial Metabolomics: Best Practices and Troubleshooting

Mar 09, 2026

Learn tissue-specific cryosectioning best practices for spatial metabolomics, including embedding, temperature control, section thickness, troubleshooting, and MSI sample prep.

Spatial Metabolomics Ion Mode Selection: Positive vs. Negative Polarity in MALDI-MSI and DESI-MSI

Mar 06, 2026

Learn how to choose positive or negative ion mode in spatial metabolomics MSI. This guide explains polarity selection for MALDI-MSI and DESI-MSI based on metabolite chemistry and experimental goals.

Core Instruments and Platforms for Spatial Metabolomics: MALDI-MSI, DESI-MSI, and SIMS

Mar 04, 2026

Learn how MALDI-MSI, DESI-MSI, and SIMS compare for spatial metabolomics—core hardware, resolution vs. coverage trade-offs, and a practical guide to choosing the right platform.

Spatial Metabolomics Sample Preparation: Cryosectioning vs. Pressing vs. Imprinting for MSI

Feb 24, 2026

Choose the right spatial metabolomics sample prep method—cryosectioning, pressing, or imprinting—with a clear comparison and decision guide for MSI.

Unlocking Plant Development: A Metabolic Map from Seed to Maturity with Spatial Metabolomics

Feb 18, 2026

Build a plant "metabolic map" from seed to senescence with spatial metabolomics (MSI)—see where metabolites change and how to design robust experiments.

From "Average" to "Tissue Maps": The Evolution and Future Trends of Spatial Metabolomics

Feb 04, 2026

Spatial metabolomics turns tissue "averages" into metabolic maps. Learn key technologies, use cases, future trends, and how to plan a successful study.

Mass Spectrometry Imaging (MSI): A Comprehensive Guide to Techniques, Applications, and Future Trends

Jan 15, 2026

Learn how Mass Spectrometry Imaging (MSI) maps molecules in tissue—compare MALDI, DESI, and SIMS, follow the core workflow, and explore key applications and future trends.

An Overview of Single-Cell Spatial Multi-Omics: Advancing Biological Research and Disease Understanding

Dec 16, 2025

Learn how single-cell spatial multi-omics integrates genomics, transcriptomics, proteomics and metabolomics to dissect cell heterogeneity and accelerate disease research.

Comprehensive Guide to Single-Cell Sorting Methods: Flow Cytometry, Magnetic Beads, and Density Gradients

Dec 11, 2025

Compare FACS, MACS and density gradient centrifugation for single-cell sorting in multi-omics studies, with use cases, pros, cons and a clear decision guide.

Integrating Spatial Transcriptomics and Metabolomics for Spatial Omics Discovery

Dec 08, 2025

Learn how to integrate spatial transcriptomics and metabolomics to resolve tumor microenvironments, handle multi-omics challenges, and accelerate translational research.

Spatial Metabolomics with MALDI-MSI: Workflow & Applications

Dec 05, 2025

Learn how MALDI-MSI powers spatial metabolomics, from tissue preparation to data analysis, with real examples in cancer, neuroscience, and drug development.

Comprehensive Overview of Single-Cell Proteomics: Methods, Technologies, and Workflow

Dec 02, 2025

Learn how single-cell proteomics works, compare antibody vs mass spectrometry approaches, and see which technologies fit your research workflow.