Proteomics

Online Webiner - From Proteome to Complexome: Unveiling the Next Frontier in Proteogenomics

Nov 18, 2025

Live webinar — Nov 18, 9:00–10:00 AM EST (online). Discover how AI deconvolves protein complexes from large-scale affinity proteomics to reveal causal biomarkers and drug targets. Join our live webinar.

Interactome & Interactomics: Mapping Protein Interaction Networks in Biology and Medicine

Mar 10, 2026

Learn what interactomics is, how protein interaction networks are mapped, and which MS-based methods help reveal disease mechanisms, drug targets, and functional biology.

PTM Proteomics Analysis Workflow: Variable Modifications, Site Localization, and FDR Control

Mar 09, 2026

Learn how to improve PTM proteomics analysis with DIA workflows, smarter variable modification settings, confident site localization, and rigorous FDR control.

Secretomics: Decoding the Secreted Proteome for Extracellular Communication

Mar 06, 2026

Learn what secretomics is, how secretome analysis works, and how mass spectrometry reveals extracellular signaling proteins for biomarker discovery and drug development.

Proteomics Data Normalization: How to Remove Batch Effects and Non-biological Bias

Mar 04, 2026

Learn how to spot, prevent, and correct batch effects in proteomics—plus a practical workflow and method-by-method guidance for reliable quant.

Data Calibration in TMT/iTRAQ Proteomics: How to Identify and Correct Channel Interference and Ratio Compression

Feb 28, 2026

Learn how to spot and fix TMT/iTRAQ channel interference and ratio compression—with practical QC red flags and calibration strategies (internal reference and mixed-sample/reference-channel) to improve quantitative accuracy.

Bottom-up vs Top-down vs Middle-down Proteomics: How to Choose the Right Strategy for PTM Analysis

Feb 26, 2026

Learn how bottom-up, top-down, and middle-down proteomics differ for PTM analysis—and how to choose the right strategy for PTM site localization, proteoform context, throughput, and PTM crosstalk.

Protein Subcellular Localization: Why a Protein's "Workplace" Matters

Feb 20, 2026

Learn how protein location controls function, how mislocalization drives disease, and which spatial proteomics tools map proteins across organelles.

Phosphopeptide Enrichment for Phosphoproteomics: TiO2 vs IMAC vs Antibody-Based Methods

Feb 11, 2026

Learn how TiO2, IMAC, and antibody-based enrichment differ in specificity, recovery, and bias—plus a practical framework to choose the best phosphopeptide enrichment workflow for your study.

Peptide-Spectrum Matching (PSM): The Core of Proteomics Database Search Algorithms

Feb 11, 2026

Learn how peptide-spectrum matching (PSM) works in proteomics database search—from spectrum preprocessing and candidate generation to scoring models (SEQUEST, Mascot, Andromeda) and ML rescoring (Percolator, Prosit).

FDR Control in Proteomics: Principles, Calculation Methods, and Threshold Selection

Feb 10, 2026

Learn how FDR control works in proteomics—Target-Decoy basics, peptide→protein FDR workflows, “picked” FDR, and how to choose the right cutoff for confident IDs.

Peptidomics: Unlocking the Hidden Language of the Proteome for Precision Medicine

Feb 05, 2026

Peptidomics explained: what it is, how LC–MS/MS workflows work, and how endogenous peptides enable biomarker discovery, immunopeptidomics, and peptide drug development in precision medicine.

Cell Surface Proteomics (Surfaceome) Guide: Definition, Workflow, and Translational Applications

Feb 04, 2026

Map the cell "surfaceome" to uncover biomarkers and drug targets. Learn enrichment strategies, LC–MS workflows, and real-world applications in oncology and immunotherapy.

Choosing the Best Proteomics Quantification Strategy: A Comprehensive Guide

Feb 02, 2026

Compare label-based, label-free, and targeted proteomics. Learn to choose the right quantification strategy for discovery or validation based on your specific research goals.

Best Practices for Blood Proteomics Sample Prep: Selecting Anticoagulants and Optimizing Pre-analytical Variables

Jan 30, 2026

Learn how selecting the right anticoagulant and optimizing pre-analytical variables can enhance plasma proteomics analysis. This guide explores the best practices for blood sample preparation to ensure accurate, reliable proteomic data.

Bypassing "Undruggable" Targets: How Phosphoproteomics Illuminates Downstream Pathways for Cancer Therapy

Jan 29, 2026

Discover how phosphoproteomics reveals actionable targets in cancer therapy. Learn how measuring phosphorylation dynamics helps overcome undruggable drivers, uncovers druggable pathways, and informs combination therapies for more effective cancer treatment.

How to Choose the Right Proteomics Technology? A Decision Guide from Sample to Goal

Jan 29, 2026

Explore how to choose the right proteomics technology based on sample types and research goals. Learn the key differences between DDA, DIA, TMT/iTRAQ, and PRM/SRM to optimize your proteomics workflow.

Quantitative Proteomics: Pioneering Techniques and Future Directions

Jan 28, 2026

Discover the latest techniques in quantitative proteomics, including mass spectrometry, isotope labeling, label-free quantification, and emerging technologies like Olink and SomaScan. Learn how these methods enable precise protein quantification for advanced biomarker discovery, clinical applications, and more.

From Biomarkers to Mechanisms: How Proteomics Is Reshaping Metabolic Disease Studies

Jan 26, 2026

Discover how proteomics improves metabolic disease subtyping, risk prediction, causal target discovery, and blood-based monitoring for T2D and NAFLD/MASH.

Unlocking the Lactylome: Bridging Metabolism, Epigenetics, and Gene Expression through Protein Lactylation

Jan 23, 2026

Protein lactylation (Kla) connects lactate metabolism to epigenetics. Learn the writers/erasers, lactylome functions, and how to study lactylation with MS-based proteomics.